NAD-ME 抗体 (AA 340-390)
Quick Overview for NAD-ME 抗体 (AA 340-390) (ABIN6991980)
抗原
See all NAD-ME 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-390
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特异性
- ME2 antibody is human specific. At least two isoforms of ME2 are known to exist, this antibody will detect both isoforms. ME2 antibody is predicted not to cross-react with ME1.
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纯化方法
- ME2 antibody is affinity chromatography purified via peptide column.
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免疫原
- ME2 antibody was raised against a 17 amino acid peptide near the center of human ME2. The immunogen is located within amino acids 340 - 390 of ME2.
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亚型
- IgG
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anti-NAD Dependent Malate Dehydrogenase (NAD-ME) antibody
NAD-ME 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (N-Term) antibodyNAD-ME 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (AA 522-556), (C-Term) antibodyNAD-ME 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 970CT2-1-1-2 unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (Internal Region) antibodyNAD-ME 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (AA 220-479) antibodyNAD-ME 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) antibodyNAD-ME 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (AA 296-424) antibodyNAD-ME 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (AA 38-87) antibodyNAD-ME 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) antibodyNAD-ME 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NAD Dependent Malate Dehydrogenase (NAD-ME) (AA 527-556), (C-Term) antibodyNAD-ME 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32070 unconjugated
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应用备注
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ME2 antibody can be used for detection of ME2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ME2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ME2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))
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别名
- ME2
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背景
- ME2 is a homotetrameric, mitochondrial NAD-dependent malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate (1). It is related to malic enzyme 1 (ME1), a cytoplasmic NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis (2). The expression of both malic enzymes is reciprocally regulated by p53, this regulation has been shown to modulate metabolism and senescence (3). Certain single-nucleotide polymorphism haplotypes of the ME2 gene have been shown to increase the risk for idiopathic generalized epilepsy (4).
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分子量
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Predicted: 64 kDa
Observed: 60 kDa -
基因ID
- 4200
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NCBI登录号
- NP_002387
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UniProt
- P23368
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途径
- Production of Molecular Mediator of Immune Response
抗原
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