MAPKSP1 抗体 (AA 40-90)
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Quick Overview for MAPKSP1 抗体 (AA 40-90) (ABIN6991975)
抗原
See all MAPKSP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90
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特异性
- LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist, this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.
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纯化方法
- LAMTOR3 antibody is affinity chromatography purified via peptide column.
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免疫原
- LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.
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亚型
- IgG
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应用备注
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LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LAMTOR3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
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别名
- LAMTOR3
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背景
- The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
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分子量
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Predicted: 14 kDa
Observed: 13 kDa -
基因ID
- 8649
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NCBI登录号
- NP_068805
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UniProt
- Q9UHA4
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途径
- PI3K-Akt Signaling
抗原
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