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SUZ12 抗体 (AA 400-450)

This anti-SUZ12 antibody is a 兔 多克隆 antibody detecting SUZ12 in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6991970
发货至: 中国

Quick Overview for SUZ12 抗体 (AA 400-450) (ABIN6991970)

抗原

See all SUZ12 抗体
SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

适用

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宿主

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克隆类型

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多克隆

标记

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This SUZ12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 400-450

    特异性

    SUZ12 antibody is human specific.

    纯化方法

    SUZ12 antibody is affinity chromatography purified via peptide column.

    免疫原

    SUZ12 antibody was raised against a 19 amino acid peptide near the center of human SUZ12. The immunogen is located within amino acids 400 - 450 of SUZ12.

    亚型

    IgG
  • 应用备注

    SUZ12 antibody can be used for detection of SUZ12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SUZ12 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SUZ12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

    别名

    SUZ12

    背景

    The Polycomb group (PcG) genes contribute to the maintenance of cell identity, cell cycle regulation and oncogenesis (1). SUZ12 (suppressor of zeste 12) is a 90 - 95 kDa member of the polycomb group of transcriptional regulators (2). It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. It contains one C2H2-type zinc finger region and a C-terminal VEFS-box (3,4). SUZ12 is overexpressed in breast and colon cancer. SUZ12 may be a cause of endometrial stromal tumors (5).

    分子量

    Predicted: 81 kDa

    Observed: 96 kDa

    基因ID

    23512

    NCBI登录号

    NP_056170

    UniProt

    Q15022
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