UCP1 抗体 (C-Term)
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北京 101111
Quick Overview for UCP1 抗体 (C-Term) (ABIN6991968)
抗原
See all UCP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- UCP1 antibody is human, mouse and rat reactive.
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纯化方法
- UCP1 antibody is affinity chromatography purified via peptide column.
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免疫原
- UCP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human UCP1 (GenBank accession. The immunogen is located within the last 50 amino acids of UCP1.
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亚型
- IgG
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应用备注
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UCP1 antibody can be used for detection of UCP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- UCP1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- UCP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- UCP1 (Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1))
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别名
- UCP1
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背景
- The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP) (1). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells (1). UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat (1).
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分子量
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Predicted: 34 kDa
Observed: 35 kDa -
基因ID
- 7350
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NCBI登录号
- NP_068605
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UniProt
- P25874
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途径
- Proton Transport, Brown Fat Cell Differentiation
抗原
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