ARR3 抗体 (C-Term)
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北京 101111
Quick Overview for ARR3 抗体 (C-Term) (ABIN6991953)
抗原
See all ARR3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ARR3 antibody is human, mouse and rat reactive. At least three isoforms of ARR3 are known to exist. This antibody is predicted to not cross-react with other members of the arrestin protein family.
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纯化方法
- ARR3 antibody is affinity chromatography purified via peptide column.
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免疫原
- ARR3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ARR3. The immunogen is located within the last 50 amino acids of ARR3.
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亚型
- IgG
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anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibody
Verified ARR3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-359) antibodyARR3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D7 unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibodyARR3 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-260) antibodyARR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 77-109) antibodyARR3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53545 unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (C-Term) antibodyARR3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 131-180) antibodyARR3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Arrestin 3, Retinal (X-Arrestin) (ARR3) (AA 1-359) antibodyARR3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ARR3 antibody can be used for detection of ARR3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ARR3 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ARR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
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别名
- ARR3
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背景
- Arrestin 3 (ARR3) belongs to the Arrestin family of proteins that function as negative regulators of G protein-coupled receptor (GPCR) signaling (1,2). ARR3 binds the c-Jun N-terminal kinase 3 (JNK3) and scaffolds the apoptosis signal-regulating kinase 1 (ASK1)-MAPK kinase4-JNK3 cascade in a receptor-independent fashion, promoting JNK3 phosphorylation (3,4). ARR3 also mediates the internalization of the C-C chemokine receptor CCR7 upon the binding of its ligand CCL19, but not CCL21, suggesting that it helps mediate CCR7 receptor desensitization (5).
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分子量
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Predicted: 43 kDa
Observed: 47 kDa -
基因ID
- 407
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NCBI登录号
- NP_004303
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UniProt
- P36575
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途径
- Phototransduction, Thromboxane A2 Receptor Signaling
抗原
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