AQP2 抗体 (C-Term)
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Quick Overview for AQP2 抗体 (C-Term) (ABIN6991948)
抗原
See all AQP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family.
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纯化方法
- AQP2 antibody is affinity chromatography purified via peptide column.
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免疫原
- AQP2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2. The immunogen is located within the last 50 amino acids of AQP2.
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亚型
- IgG
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应用备注
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AQP2 antibody can be used for detection of AQP2 by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- AQP2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- AQP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))
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别名
- AQP2
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背景
- Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorbtion (1). AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles (2). Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus (3).
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分子量
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Predicted: 30 kDa
Observed: 28 kDa -
基因ID
- 359
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NCBI登录号
- NP_000477
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UniProt
- P41181
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途径
- Response to Water Deprivation
抗原
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