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AQP2 抗体 (C-Term)

This anti-AQP2 antibody is a 兔 多克隆 antibody detecting AQP2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6991948
发货至: 中国

Quick Overview for AQP2 抗体 (C-Term) (ABIN6991948)

抗原

See all AQP2 抗体
AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This AQP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    特异性

    AQP2 antibody is human, mouse and rat reactive. This antibody is predicted to not cross-react with other members of the aquaporin protein family.

    纯化方法

    AQP2 antibody is affinity chromatography purified via peptide column.

    免疫原

    AQP2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AQP2. The immunogen is located within the last 50 amino acids of AQP2.

    亚型

    IgG
  • 应用备注

    AQP2 antibody can be used for detection of AQP2 by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    AQP2 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    AQP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    AQP2 (Aquaporin 2 (Collecting Duct) (AQP2))

    别名

    AQP2

    背景

    Aquaporins are membrane proteins that serve in the transfer of water and small solutes across cellular membranes. One such aquaporin, aquaporin-2 (AQP2) is located in the kidney collecting tubule and plays a critical role in water reabsorbtion (1). AQP2 is mainly localized in intracellular vesicles but upon stimulation with anti-diuretic hormone (ADH), AQP2 is translocated to the apical plasma membrane by exocytic fusion of AQP2-bearing vesicles (2). Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus (3).

    分子量

    Predicted: 30 kDa

    Observed: 28 kDa

    基因ID

    359

    NCBI登录号

    NP_000477

    UniProt

    P41181

    途径

    Response to Water Deprivation
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