PHC3 抗体 (N-Term)
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北京 101111
Quick Overview for PHC3 抗体 (N-Term) (ABIN6991943)
抗原
See all PHC3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 240-290, N-Term
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特异性
- PHC3 antibody is human, mouse and rat specific. At least six isoforms of PHC3 are known to exist.
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纯化方法
- PHC3 antibody is affinity chromatography purified via peptide column.
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免疫原
- PHC3 antibody was raised against a 19 amino acid peptide near the amino terminus of human PHC3. The immunogen is located within amino acids 240 - 290 of PHC3.
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亚型
- IgG
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应用备注
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PHC3 antibody can be used for detection of PHC3 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PHC3 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PHC3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- PHC3 (Polyhomeotic Homolog 3 (PHC3))
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别名
- PHC3
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背景
- Polycomb group (PcG) proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes throughout development (1). PHC3 (Polyhomeotic-like protein 3), also known as Early development regulatory protein 3, is a 983 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex (2). PRC1 complex acts via chromatin remodeling and modification of histones. PHC3 contains 1 FCS-type zinc finger and SAM (sterile alpha motif) domain (2-3). PHC 3 has been regarded as a candidate tumor suppressor of osteosarcoma (4).
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分子量
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Predicted: 109 kDa
Observed: 120 kDa -
基因ID
- 80012
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NCBI登录号
- NP_079223
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UniProt
- Q8NDX5
抗原
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