Dynamin 1-Like 抗体 (AA 530-580)
Quick Overview for Dynamin 1-Like 抗体 (AA 530-580) (ABIN6991941)
抗原
See all Dynamin 1-Like (DNM1L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 530-580
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特异性
- DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist, this antibody will detect the two longest isoforms.
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纯化方法
- DNM1L antibody is affinity chromatography purified via peptide column.
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免疫原
- DNM1L antibody was raised against a 19 amino acid peptide near the center of human DNM1L. The immunogen is located within amino acids 530 - 580 of DNM1L.
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亚型
- IgG
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应用备注
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DNM1L antibody can be used for detection of DNM1L by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DNM1L antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DNM1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Dynamin 1-Like (DNM1L)
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别名
- DNM1L
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背景
- The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).
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分子量
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Predicted: 81 kDa
Observed: 80 kDa -
基因ID
- 10059
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NCBI登录号
- NP_036192
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UniProt
- O00429
抗原
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