FIL1d 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for FIL1d 抗体 (C-Term) (ABIN6991918)
抗原
See all FIL1d 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- IL-36RN antibody is human and mouse reactive. At least two isoforms of IL-36RN are known to exist
-
纯化方法
- IL-36RN antibody is affinity chromatography purified via peptide column.
-
免疫原
- IL-36RN antibody was raised against a 19 amino acid peptide near the carboxy terminus of human IL-36RN. The immunogen is located within the last 50 amino acids of IL-36RN.
-
亚型
- IgG
-
-
-
-
应用备注
-
IL-36RN antibody can be used for detection of IL-36RN by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- IL-36RN antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- IL-36RN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- FIL1d (Interleukin 1 delta (FIL1d))
-
别名
- IL-36RN
-
背景
- IL-36RN is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36RN specifically inhibits the activation of NF-kappaB induced IL-36A (2). The opposing activities of these cytokines have been suggested to be involved in the regulation of skin inflammation (3). Like the IL-36 cytokines (IL-36A, IL-36B and IL-36G), IL-36RN requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (4).
-
分子量
- Observed Molecular Weight: 24 kDa
-
基因ID
- 26525
-
NCBI登录号
- NP_775262
-
UniProt
- Q9UBH0
抗原
-