FIL1h 抗体 (C-Term)
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Quick Overview for FIL1h 抗体 (C-Term) (ABIN6991916)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- IL-36B antibody is human specific. At least two isoforms of IL-36B are known to exist, this antibody will only detect the longer isoform. IL-36B antibody will not cross-react with IL-36A or IL-36G.
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纯化方法
- IL-36B antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-36B antibody was raised against a 16 amino acid peptide near the carboxy terminus of human IL-36B. The immunogen is located within the last 50 amino acids of IL-36B.
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亚型
- IgG
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应用备注
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IL-36B antibody can be used for detection of IL-36B by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-36B antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-36B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- FIL1h (Interleukin 1 eta (FIL1h))
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别名
- IL-36B
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背景
- IL-36B is is a member of the interleukin 1 cytokine family whose gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2 (1). IL-36B is thought to activate the NF-kappaB pathway through IL-1 receptor family members IL-1RL2 and IL-1RAcP (2). Like the related proteins IL-36A and IL-36G, IL-36B requires post-translational processing for full agonist activity, but the cleavage mechanism is currently unknown (3). The IL-36 cytokines have been suggested to amplify Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells (4).
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分子量
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Predicted: 18 kDa
Observed: 17 kDa -
基因ID
- 27177
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NCBI登录号
- NP_055253
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UniProt
- Q9NZH7
抗原
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