IL-1F10 antibody is human, mouse and rat reactive. Two isoforms of IL-1F10 exist.
纯化方法
IL-1F10 antibody is affinity chromatography purified via peptide column.
免疫原
Anti-IL-1F10 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human IL-1F10. The immunogen is located within the last 50 amino acids of IL-1F10.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
IL-1F10 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
IL-1F10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
IL1F10
(Interleukin 1 Family, Member 10 (Theta) (IL1F10))
别名
IL-1F10
背景
The cytokine IL-1 is responsible for initiating a variety of activities through the activation of transcription factors, NF-kappa B and AP-1, thereby promoting host response to injury or infection (1). IL-1F10 (Interleukin-1 family member 10), also known as FIL1T, IL1HY2 or FKSG75, is highly expressed in the skin, spleen and proliferating B-cells of the tonsil (2). IL-1F10 binds soluble IL-1 receptor type 1, and is one of nine Interleukin 1 families clustered on chromosome 2, where it is thought to participate in the regulation of adapted and innate immune responses (3). IL-1F10 and IL-1RN polymorphisms may play an important role in the susceptibility to developing rheumatoid arthritis (4).