IL1RL2 抗体 (AA 260-310)
Our Local Distributor
北京 101111
Quick Overview for IL1RL2 抗体 (AA 260-310) (ABIN6991913)
抗原
See all IL1RL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 260-310
-
特异性
- IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist, this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.
-
纯化方法
- IL-1RL2 antibody is affinity chromatography purified via peptide column.
-
免疫原
- IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2. The immunogen is located within amino acids 260 - 310 of IL-1RL2.
-
亚型
- IgG
-
-
-
-
应用备注
-
IL-1RL2 antibody can be used for detection of IL-1RL2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- IL-1RL2 antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- IL-1RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))
-
别名
- IL-1RL2
-
背景
- IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation response (3).
-
分子量
-
Predicted: 61 kDa
Observed: 55 kDa -
基因ID
- 8808
-
NCBI登录号
- NP_003845
-
UniProt
- Q9HB29
抗原
-