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IL1RL2 抗体 (AA 260-310)

This anti-IL1RL2 antibody is a 兔 多克隆 antibody detecting IL1RL2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991913
发货至: 中国

Quick Overview for IL1RL2 抗体 (AA 260-310) (ABIN6991913)

抗原

See all IL1RL2 抗体
IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IL1RL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 260-310

    特异性

    IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist, this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.

    纯化方法

    IL-1RL2 antibody is affinity chromatography purified via peptide column.

    免疫原

    IL-1RL2 antibody was raised against a 16 amino acid peptide near the center of human IL-1RL2. The immunogen is located within amino acids 260 - 310 of IL-1RL2.

    亚型

    IgG
  • 应用备注

    IL-1RL2 antibody can be used for detection of IL-1RL2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-1RL2 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-1RL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

    别名

    IL-1RL2

    背景

    IL-1RL2 is a member of the interleukin 1 receptor family, but it is incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity (1). Together with IL-1RAcP, it can bind members of the IL-36 cytokine family, leading to activation of the NF-kappaB pathway (2). IL-1RL2 can also bind to IL-1F10, resulting in a decreased product of Th17 cytokines in response to immunological or LPS challenge, suggesting that one potential role of IL-1RL2 may be to modulate the immune and inflammation response (3).

    分子量

    Predicted: 61 kDa

    Observed: 55 kDa

    基因ID

    8808

    NCBI登录号

    NP_003845

    UniProt

    Q9HB29
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