SOGA1 抗体 (C-Term)
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北京 101111
Quick Overview for SOGA1 抗体 (C-Term) (ABIN6991908)
抗原
See all SOGA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- SOGA1 antibody is human specific. At least four isoforms of SOGA1 are known to exist.
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纯化方法
- SOGA1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SOGA1 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human SOGA. The immunogen is located within the last 50 amino acids of SOGA1 .
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亚型
- IgG
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应用备注
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SOGA1 antibody can be used for detection of SOGA1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SOGA1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SOGA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SOGA1 (Suppressor of Glucose, Autophagy Associated 1 (SOGA1))
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别名
- SOGA1
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背景
- The recently identified protein suppressor of glucose by autophagy protein 1 (SOGA1) has been found to be involved in the regulation of autophagy (1). SOGA1 is thought to contribute to adiponectin-mediated insulin-dependent inhibition of autophagy during the activation of adenosine monophosphate kinase (AMPK) (1,2). SOGA1 contains an internal signal peptide that enables the secretion of a circulating fragment of SOGA1, providing a surrogate marker for intracellular SOGA1 levels (2). Knockdown of SOGA1 elevated glucose production in primary hepatocytes indicates that SOGA1 is an inhibitor of glucose production. It thus might be useful as a novel therapeutic target for diabetes (3).
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分子量
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Predicted: 183 kDa
Observed: 200kDa -
基因ID
- 140710
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NCBI登录号
- NP_954650
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UniProt
- O94964
抗原
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