ERAP2 抗体 (N-Term)
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Quick Overview for ERAP2 抗体 (N-Term) (ABIN6991900)
抗原
See all ERAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-160, N-Term
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特异性
- ERAP2 antibody is human reactive. Multiple isoforms of ERAP2 are known to exist. ERAP2 antibody is predicted to not cross-react with ERAP1.
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纯化方法
- ERAP2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ERAP2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ERAP2. The immunogen is located within amino acids 110 - 160 of ERAP2 .
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亚型
- IgG
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应用备注
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ERAP2 antibody can be used for detection of ERAP2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ERAP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ERAP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))
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别名
- ERAP2
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背景
- The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer (1). Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response (reviewed in 3).
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分子量
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Predicted: 106 kDa
Observed: 120kDa -
基因ID
- 64167
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NCBI登录号
- NP_071745
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UniProt
- Q6P179
抗原
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