beta-2 Microglobulin 抗体 (C-Term)
Quick Overview for beta-2 Microglobulin 抗体 (C-Term) (ABIN6991888)
抗原
See all beta-2 Microglobulin (B2M) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- B2M antibody is human reactive.
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纯化方法
- B2M Antibody is affinity chromatography purified via peptide column.
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免疫原
- B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M. The immunogen is located within the last 50 amino acids of B2M.
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亚型
- IgG
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应用备注
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B2M antibody can be used for detection of B2M by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- B2M Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- B2M antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
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别名
- B2M
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背景
- B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
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分子量
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Predicted: 13 kDa
Observed: 12 kDa -
基因ID
- 567
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NCBI登录号
- NP_004039
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UniProt
- P61769
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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