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beta-2 Microglobulin 抗体 (C-Term)

This anti-beta-2 Microglobulin antibody is a 兔 多克隆 antibody detecting beta-2 Microglobulin in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6991888
发货至: 中国

Quick Overview for beta-2 Microglobulin 抗体 (C-Term) (ABIN6991888)

抗原

See all beta-2 Microglobulin (B2M) 抗体
beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

适用

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克隆类型

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多克隆

标记

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This beta-2 Microglobulin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    特异性

    B2M antibody is human reactive.

    纯化方法

    B2M Antibody is affinity chromatography purified via peptide column.

    免疫原

    B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M. The immunogen is located within the last 50 amino acids of B2M.

    亚型

    IgG
  • 应用备注

    B2M antibody can be used for detection of B2M by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    B2M Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    B2M antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

    别名

    B2M

    背景

    B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).

    分子量

    Predicted: 13 kDa

    Observed: 12 kDa

    基因ID

    567

    NCBI登录号

    NP_004039

    UniProt

    P61769

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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