BimEL 抗体 (N-Term)
适用: 大鼠, 人, 小鼠
WB, ELISA, ICC, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all BimEL products
- BimEL
- 抗原表位
- AA 20-70, N-Term
- 适用
- 大鼠, 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BimEL antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.
- 纯化方法
- Bim EL Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim. The immunogen is located within amino acids 20 - 70 of Bim EL.
- 亚型
- IgG
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- 应用备注
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Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- BimEL
- 别名
- Bim EL (BimEL 产品)
- 背景
- Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
- 分子量
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Predicted: 22 kDa
Observed: 24 kDa - 基因ID
- 10018
- NCBI登录号
- NP_619527
- UniProt
- O43521
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