BimEL 抗体 (N-Term)
This anti-BimEL antibody is a 兔 多克隆 antibody detecting BimEL in WB, ELISA, ICC 和 IF. Suitable for 大鼠, 人 和 小鼠.
Quick Overview for BimEL 抗体 (N-Term) (ABIN6991882)
抗原
BimEL
适用
大鼠, 人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This BimEL antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
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抗原表位
- AA 20-70, N-Term
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特异性
- Bim EL antibody is human and mouse reactive. Multiple isoforms of Bim are known to exist, this antibody only detects the Bim EL isoform.
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纯化方法
- Bim EL Antibody is affinity chromatography purified via peptide column.
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免疫原
- Bim EL antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human Bim. The immunogen is located within amino acids 20 - 70 of Bim EL.
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亚型
- IgG
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应用备注
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Bim EL antibody can be used for detection of Bim EL by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Bim EL Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Bim EL antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- BimEL
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别名
- Bim EL
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背景
- Bim EL Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. Bim, also known as Bcl-2-like protein 11, is a pro-apoptotic member of this family and interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Multiple isoforms of Bim are known to exist, with Bim EL being the longest isoform (1,2).
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分子量
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Predicted: 22 kDa
Observed: 24 kDa -
基因ID
- 10018
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NCBI登录号
- NP_619527
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UniProt
- O43521
抗原
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