IL17RA 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for IL17RA 抗体 (N-Term) (ABIN6991881)
抗原
See all IL17RA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 150-200, N-Term
-
特异性
- IL-17RA antibody is human, mouse and rat reactive. Multiple isoforms of IL-17RA are known to exist. This antibody is predicted to not cross-react with other IL-17 receptor subunits.
-
纯化方法
- IL-17RA Antibody is affinity chromatography purified via peptide column.
-
免疫原
- IL-17RA antibody was raised against an 18 amino acid peptide near the amino terminus of human IL-17RA. The immunogen is located within amino acids 150 - 200 of IL-17RA.
-
亚型
- IgG
-
-
-
-
应用备注
-
IL-17RA antibody can be used for detection of IL-17RA by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- IL-17RA Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- IL-17RA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- IL17RA (Interleukin 17 Receptor A (IL17RA))
-
别名
- IL-17RA
-
背景
- IL-17RA Antibody: Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes (1). It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a ubiquitous type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F (1,2). IL-17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis (3,4). Defects in IL-17RA are the cause of familial candidiasis type 5 (CANDF5) which is a rare disorder with altered immune responses and impaired clearance of fungal infections (5).
-
分子量
-
Predicted: 95 kDa
Observed: 135 kDa -
基因ID
- 23765
-
NCBI登录号
- NP_055154
-
UniProt
- Q96F46
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-