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Lipin 1 抗体 (C-Term)

This anti-Lipin 1 antibody is a 兔 多克隆 antibody detecting Lipin 1 in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6991876
发货至: 中国

Quick Overview for Lipin 1 抗体 (C-Term) (ABIN6991876)

抗原

See all Lipin 1 (LPIN1) 抗体
Lipin 1 (LPIN1)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Lipin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    LPIN1 antibody is human and mouse reactive. At least four isoforms of LPIN1 are known to exist.

    纯化方法

    LPIN1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    LPIN1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LPIN1. The immunogen is located within the last 50 amino acids of LPIN1.

    亚型

    IgG
  • 应用备注

    LPIN1 antibody can be used for detection of LPIN1 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    LPIN Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    LPIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    Lipin 1 (LPIN1)

    别名

    LPIN1

    背景

    LPIN1 Antibody: LPIN1, also known as PAP1, is a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol (reviewed in 1). LPIN1 is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism (1,2). Mutations in LPIN1 are associated with metabolic diseases such as type 2 diabetes and recurrent acute myoglobinuria (3,4) and it is also a candidate for several human lipodystrophy syndromes (5).

    分子量

    Predicted: 107 kDa

    Observed: 125 kDa

    基因ID

    23175

    NCBI登录号

    NP_001248357

    UniProt

    Q14693

    途径

    Monocarboxylic Acid Catabolic Process
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