DAP 抗体 (C-Term)
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北京 101111
Quick Overview for DAP 抗体 (C-Term) (ABIN6991874)
抗原
See all DAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- DAP antibody is human, mouse and rat reactive.
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纯化方法
- DAP Antibody is affinity chromatography purified via peptide column.
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免疫原
- DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP. The immunogen is located within the last 50 amino acids of DAP.
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亚型
- IgG
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应用备注
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DAP antibody can be used for detection of DAP by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DAP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DAP antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DAP (Death-Associated Protein (DAP))
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别名
- DAP
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背景
- DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15 kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51, under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2).
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分子量
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Predicted: 11 kDa
Observed: 11 kDa -
基因ID
- 1611
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NCBI登录号
- NP_004385
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UniProt
- P51397
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途径
- Positive Regulation of Endopeptidase Activity, Feeding Behaviour
抗原
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