At least two isoforms of TRIM24 are known to exist.
纯化方法
TRIM24 Antibody is affinity chromatography purified via peptide column.
免疫原
TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.
TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
TRIM24
(Tripartite Motif Containing 24 (TRIM24))
别名
TRIM24
背景
TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).