TRIM24 抗体 (AA 530-580)
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北京 101111
Quick Overview for TRIM24 抗体 (AA 530-580) (ABIN6991871)
抗原
See all TRIM24 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 530-580
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特异性
- At least two isoforms of TRIM24 are known to exist.
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纯化方法
- TRIM24 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TRIM24 antibody was raised against a 19 amino acid peptide near the center of human TRIM24. The immunogen is located within amino acids 530 - 580 of TRIM24.
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亚型
- IgG
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应用备注
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TRIM24 antibody can be used for detection of TRIM24 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TRIM24 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TRIM24 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- TRIM24 (Tripartite Motif Containing 24 (TRIM24))
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别名
- TRIM24
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背景
- TRIM24 Antibody: TRIM24 (TIF1), a member of the tripartite motif (TRIM) family, plays a role in the regulation of cell proliferation and apoptosis. TRIM24 localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The TRIM motif includes three zinc-binding domains (RING, B-box type 1 and B-box type 2) and a coiled-coil region. TIF1 mediates transcriptional events by interactions with the AF2 region of several nuclear receptors, such as the estrogen, retinoic acid and vitamin D3 receptors. Defects in TRIM24 are a cause of thyroid papillary carcinoma (TPC).
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分子量
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Predicted: 112, 116
Observed: 108, 1 of 2 isoforms kDa -
基因ID
- 8805
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NCBI登录号
- NP_056989
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UniProt
- O15164
抗原
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