DIS3 抗体 (N-Term)
Quick Overview for DIS3 抗体 (N-Term) (ABIN6991861)
抗原
See all DIS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-140, N-Term
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特异性
- Multiple isoforms of DIS3 are known to exist.
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纯化方法
- DIS3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. The immunogen is located within amino acids 90 - 140 of DIS3.
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亚型
- IgG
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anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibody
DIS3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 1-958) antibodyDIS3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 861-956) antibodyDIS3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 30-187) antibodyDIS3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 290-339) antibodyDIS3 适用: 人, 小鼠, 大鼠, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 1-280) antibodyDIS3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 295-323) antibodyDIS3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24091 unconjugated
anti-Exosome Complex Exonuclease RRP44 (DIS3) (AA 302-331), (Middle Region) antibodyDIS3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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DIS3 antibody can be used for detection of DIS3 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DIS3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DIS3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- DIS3 (Exosome Complex Exonuclease RRP44 (DIS3))
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别名
- DIS3
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背景
- DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.
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分子量
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Predicted: 105 kDa
Observed: 103 kDa -
基因ID
- 22894
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NCBI登录号
- NP_055768
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UniProt
- Q9Y2L1
抗原
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