APOE 抗体 (C-Term)
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Quick Overview for APOE 抗体 (C-Term) (ABIN6991857)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-270, C-Term
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纯化方法
- APO-E Antibody is affinity chromatography purified via peptide column.
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免疫原
- APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E. The immunogen is located within amino acids 220 - 270 of APO-E.
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亚型
- IgG
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应用备注
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APO-E antibody can be used for detection of APO-E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APO-E Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APO-E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- APOE (Apolipoprotein E (APOE))
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别名
- APO-E
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背景
- APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
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分子量
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Predicted: 35 kDa
Observed: 34 kDa -
基因ID
- 348
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NCBI登录号
- NP_000032
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UniProt
- P02649
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途径
- Regulation of Cell Size, Lipid Metabolism
抗原
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