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APOE 抗体 (C-Term)

This anti-APOE antibody is a 兔 多克隆 antibody detecting APOE in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991857
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for APOE 抗体 (C-Term) (ABIN6991857)

抗原

See all APOE 抗体
APOE (Apolipoprotein E (APOE))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This APOE antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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    AA 220-270, C-Term

    纯化方法

    APO-E Antibody is affinity chromatography purified via peptide column.

    免疫原

    APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E. The immunogen is located within amino acids 220 - 270 of APO-E.

    亚型

    IgG
  • 应用备注

    APO-E antibody can be used for detection of APO-E by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human and mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    APO-E Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    APO-E antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    APOE (Apolipoprotein E (APOE))

    别名

    APO-E

    背景

    APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    分子量

    Predicted: 35 kDa

    Observed: 34 kDa

    基因ID

    348

    NCBI登录号

    NP_000032

    UniProt

    P02649

    途径

    Regulation of Cell Size, Lipid Metabolism
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