ANKRD15 抗体 (N-Term)
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北京 101111
Quick Overview for ANKRD15 抗体 (N-Term) (ABIN6991851)
抗原
See all ANKRD15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.
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纯化方法
- KANK1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 . The immunogen is located within the first 50 amino acids of KANK1.
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亚型
- IgG
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应用备注
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KANK1 Antibody can be used for detection of KANK1 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- KANK1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- KANK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
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别名
- KANK1
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背景
- KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.
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分子量
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Predicted: 149 kDa
Observed: 150 kDa -
基因ID
- 23189
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NCBI登录号
- NP_055973
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UniProt
- Q14678
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途径
- Regulation of Actin Filament Polymerization
抗原
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