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ANKRD15 抗体 (N-Term)

This anti-ANKRD15 antibody is a 兔 多克隆 antibody detecting ANKRD15 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6991851
发货至: 中国
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Quick Overview for ANKRD15 抗体 (N-Term) (ABIN6991851)

抗原

See all ANKRD15 抗体
ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

适用

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人, 小鼠

宿主

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克隆类型

  • 9
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多克隆

标记

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This ANKRD15 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    特异性

    Two alternatively spliced transcript variants encoding different isoforms have been identified. The lower molecular weight band seen in the immunoblot is thought to be non-specific.

    纯化方法

    KANK1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    KANK1 antibody was raised against a 19 amino acid peptide near the amino terminus of human KANK1 . The immunogen is located within the first 50 amino acids of KANK1.

    亚型

    IgG
  • 应用备注

    KANK1 Antibody can be used for detection of KANK1 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    KANK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    KANK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

    别名

    KANK1

    背景

    KANK1 Antibody: Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. KANK1 (KN motif and ankyrin repeat domain-containing protein 1), also known as ANKRD15, is a 1,352 amino acid protein that contains at least 12 exons and 5 ANK repeats. It binds to beta-catenin and regulates its subcellular distribution. KANK1 is ubiquitously expressed and localizes to cytoplasm. It may function as a tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder.

    分子量

    Predicted: 149 kDa

    Observed: 150 kDa

    基因ID

    23189

    NCBI登录号

    NP_055973

    UniProt

    Q14678

    途径

    Regulation of Actin Filament Polymerization
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