CISD2 抗体 (AA 40-90)
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北京 101111
Quick Overview for CISD2 抗体 (AA 40-90) (ABIN6991848)
抗原
See all CISD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90
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纯化方法
- CISD2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2. The immunogen is located within amino acids 40 - 90 of CISD2.
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亚型
- IgG
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anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 61-135) antibody
CISD2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (AA 110-144) antibodyCISD2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51992 unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-CDGSH Iron Sulfur Domain 2 (CISD2) (N-Term) antibodyCISD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CISD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CISD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))
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别名
- CISD2
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背景
- CISD2 Antibody: Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2. CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster. CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy. CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype.
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分子量
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Predicted: 15 kDa
Observed: 15 kDa -
基因ID
- 493856
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NCBI登录号
- NP_001008389
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UniProt
- Q8N5K1
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途径
- Activation of Innate immune Response
抗原
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