WAC 抗体 (AA 210-260)
-
- 抗原 See all WAC 抗体
- WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
-
抗原表位
- AA 210-260
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This WAC antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- At least two isoforms of WAC are known to exist, this antibody will detect the larger isoform.
- 纯化方法
- WAC Antibody is affinity chromatography purified via peptide column.
- 免疫原
- WAC antibody was raised against a 19 amino acid peptide near the center of human WAC . The immunogen is located within amino acids 210 - 260 of WAC.
- 亚型
- IgG
- Top Product
- Discover our top product WAC Primary Antibody
-
anti-WW Domain Containing Adaptor with Coiled-Coil (WAC) (AA 10-102) antibody
WAC 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Adaptor with Coiled-Coil (WAC) (AA 1-320) antibodyWAC 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-WW Domain Containing Adaptor with Coiled-Coil (WAC) (AA 284-313) antibodyWAC 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB24117 unconjugated
anti-WW Domain Containing Adaptor with Coiled-Coil (WAC) (AA 291-321), (Middle Region) antibodyWAC 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WAC Antibody can be used for detection of WAC by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- WAC Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- WAC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
- 抗原
- WAC (WW Domain Containing Adaptor with Coiled-Coil (WAC))
- 别名
- WAC (WAC 产品)
- 别名
- BM-016 antibody, PRO1741 antibody, Wwp4 antibody, 1110067P07Rik antibody, A230035H12Rik antibody, AI256735 antibody, AI256776 antibody, DKFZp468H162 antibody, wac antibody, wu:fc13f04 antibody, wu:fj68f01 antibody, zgc:55755 antibody, RGD1562407 antibody, zgc:101828 antibody, WW domain containing adaptor with coiled-coil antibody, WW domain containing adaptor with coiled-coil a antibody, WW domain containing adaptor with coiled-coil b antibody, WAC antibody, Wac antibody, wac antibody, waca antibody, wacb antibody
- 背景
- WAC Antibody: The WW domain containing adaptor with coiled-coil protein (WAC) contains a WW domain that mediates protein-protein interactions and colocalizes with RNA splicing factor SC35. Further studies have indicated that WAC is a functional partner of the RNF20/40 complex that ubiquitinates Histone H2B, and that WAC regulates H2B ubiquitination. WAC targets RNF20/40 to associate with RNA polymerase II complex for H2B ubiquitination at active transcription sites. WAC-dependent transcription is also important for cell-cycle checkpoint activation in response to genotoxic stress.
- 分子量
-
Predicted: 71 kDa
Observed: 75 kDa - 基因ID
- 51322
- NCBI登录号
- NP_057712
- UniProt
- Q9BTA9
- 途径
- Chromatin Binding
-
