ERRF Antibody is affinity chromatography purified via peptide column.
免疫原
ERRF antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ERRF . The immunogen is located within the last 50 amino acids of ERRF.
C1ORF64
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 555
应用备注
ERRF Antibody can be used for detection of ERRF by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
ERRF Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
ERRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
C1orf64 (C1ORF64)
(Chromosome 1 Open Reading Frame 64 (C1ORF64))
ERRF antibody, RP11-5P18.4 antibody, steroid receptor associated and regulated protein antibody, SRARP antibody
背景
ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.