SHISA4 抗体 (AA 100-150)
This anti-SHISA4 antibody is a 兔 多克隆 antibody detecting SHISA4 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
Quick Overview for SHISA4 抗体 (AA 100-150) (ABIN6991838)
抗原
See all SHISA4 抗体
SHISA4
(Shisa Homolog 4 (SHISA4))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This SHISA4 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- AA 100-150
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特异性
- SHISA4 antibody is predicted to not cross-react with other SHISA protein family members.
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纯化方法
- SHISA4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SHISA4 antibody was raised against a 15 amino acid peptide near the center of human SHISA4 . The immunogen is located within amino acids 100 - 150 of SHISA4.
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亚型
- IgG
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anti-Shisa Homolog 4 (SHISA4) (AA 28-197) antibody
SHISA4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Shisa Homolog 4 (SHISA4) (AA 28-197) antibodySHISA4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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SHISA4 Antibody can be used for detection of SHISA4 by Western blot starting at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SHISA4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SHISA4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SHISA4 (Shisa Homolog 4 (SHISA4))
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别名
- SHISA4
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背景
- SHISA4 Antibody: SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
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分子量
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Predicted: 22 kDa
Observed: 24 kDa -
基因ID
- 149345
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NCBI登录号
- NP_937792
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UniProt
- Q96DD7
抗原
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