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SHISA3 抗体 (AA 120-170)

SHISA3 适用: 小鼠, 人, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991837
发货至: 中国
  • 抗原 See all SHISA3 抗体
    SHISA3 (Shisa Homolog 3 (SHISA3))
    抗原表位
    • 8
    • 8
    • 7
    AA 120-170
    适用
    小鼠, 人, 大鼠
    宿主
    • 15
    克隆类型
    • 15
    多克隆
    标记
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    This SHISA3 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 12
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    SHISA3 antibody is predicted to not cross-react with other SHISA protein family members.
    纯化方法
    SHISA3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    SHISA3 antibody was raised against a 15 amino acid peptide near the center of human SHISA3 . The immunogen is located within amino acids 120 - 170 of SHISA3.
    亚型
    IgG
    Top Product
    Discover our top product SHISA3 Primary Antibody
  • 应用备注
    SHISA3 Antibody can be used for detection of SHISA3 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    SHISA3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    SHISA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    SHISA3 (Shisa Homolog 3 (SHISA3))
    别名
    SHISA3 (SHISA3 产品)
    别名
    hShisa3 antibody, D830007B15Rik antibody, shisa family member 3 antibody, SHISA3 antibody, Shisa3 antibody
    背景
    SHISA3 Antibody: SHISA3 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
    分子量
    Predicted: 26 kDa

    Observed: 28 kDa
    基因ID
    152573
    NCBI登录号
    NP_001073974
    UniProt
    A0PJX4
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