SHISA3 抗体 (AA 120-170)
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北京 101111
Quick Overview for SHISA3 抗体 (AA 120-170) (ABIN6991837)
抗原
See all SHISA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 120-170
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特异性
- SHISA3 antibody is predicted to not cross-react with other SHISA protein family members.
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纯化方法
- SHISA3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SHISA3 antibody was raised against a 15 amino acid peptide near the center of human SHISA3 . The immunogen is located within amino acids 120 - 170 of SHISA3.
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亚型
- IgG
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应用备注
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SHISA3 Antibody can be used for detection of SHISA3 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SHISA3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SHISA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SHISA3 (Shisa Homolog 3 (SHISA3))
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别名
- SHISA3
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背景
- SHISA3 Antibody: SHISA3 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
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分子量
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Predicted: 26 kDa
Observed: 28 kDa -
基因ID
- 152573
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NCBI登录号
- NP_001073974
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UniProt
- A0PJX4
抗原
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