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IL-15 抗体 (AA 50-100)

This anti-IL-15 antibody is a 兔 多克隆 antibody detecting IL-15 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991820
发货至: 中国

Quick Overview for IL-15 抗体 (AA 50-100) (ABIN6991820)

抗原

See all IL-15 (IL15) 抗体
IL-15 (IL15) (Interleukin 15 (IL15))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IL-15 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 49
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    AA 50-100

    特异性

    At least two isoforms of IL-15 are known to exist.

    纯化方法

    IL-15 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal IL-15 antibody was raised against a 13 amino acid peptide near the center of human IL-15. The immunogen is located within amino acids 50 - 100 of IL-15.

    亚型

    IgG
  • 应用备注

    IL-15 antibody can be used for detection of IL-15 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-15 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-15 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    IL-15 (IL15) (Interleukin 15 (IL15))

    别名

    IL-15

    背景

    IL-15 Antibody: Interleukin 15 (IL-15) is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and IL-2 share many biological activities as both have been found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between IL-15 and IL-2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. In mouse, studies suggest that IL-15 may increase the expression of apoptosis inhibitor Bcl-xL, possibly through the transcription activation activity of STAT6, and thus prevent apoptosis.

    分子量

    18 kDa

    基因ID

    3600

    NCBI登录号

    NP_000576

    UniProt

    P40933

    途径

    JAK/STAT Signaling, Glycosaminoglycan Metabolic Process
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