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Cyclin T1 抗体 (C-Term)

This anti-Cyclin T1 antibody is a 兔 多克隆 antibody detecting Cyclin T1 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991816
发货至: 中国

Quick Overview for Cyclin T1 抗体 (C-Term) (ABIN6991816)

抗原

See all Cyclin T1 (CCNT1) 抗体
Cyclin T1 (CCNT1)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Cyclin T1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    C-Term

    纯化方法

    CCNT1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal CCNT1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human CCNT1. The immunogen is located within the last 50 amino acids of CCNT1.

    亚型

    IgG
  • 应用备注

    CCNT1 antibody can be used for detection of CCNT1 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CCNT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CCNT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    Cyclin T1 (CCNT1)

    别名

    CCNT1

    背景

    CCNT1 Antibody: Cyclins function as regulators of CDK kinases and exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin-T1 protein (CCNT1) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. CCNT1 tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing CCNT1 and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. CCNT1 and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.

    分子量

    Predicted: 80 kDa

    基因ID

    904

    NCBI登录号

    NP_001231

    UniProt

    O60563
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