CARM1 抗体 (N-Term)
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北京 101111
Quick Overview for CARM1 抗体 (N-Term) (ABIN6991814)
抗原
See all CARM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 470-520, N-Term
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纯化方法
- CARM1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal CARM1 antibody was raised against a 19 amino acid peptide near the amino terminus of human CARM1. The immunogen is located within amino acids 470 - 520 of CARM1.
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亚型
- IgG
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应用备注
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CARM1 antibody can be used for detection of CARM1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CARM1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CARM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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别名
- CARM1
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背景
- CARM1 Antibody: Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation. CARM1 functions as a transcriptional co-activator for various nuclear receptors and NF-κ,B. It has also been shown to methylate histone H3 arginines, inhibiting the binding of corepressors and protecting chromatin from deacetylation, thereby facilitating transcription.
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分子量
- Predicted: 67 kDa
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基因ID
- 10498
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NCBI登录号
- NP_954592
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UniProt
- Q86X55
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
抗原
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