JAKMIP1 抗体 (AA 260-310)
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Quick Overview for JAKMIP1 抗体 (AA 260-310) (ABIN6991799)
抗原
See all JAKMIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-310
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特异性
- Multiple isoforms of JAKMIP1 are known to exist. JAKMIP1 antibody is predicted to not cross-react with JAKMIP2.
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纯化方法
- JAKMIP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal JAKMIP1 antibody was raised against a 16 amino acid peptide near the center of human JAKMIP1. The immunogen is located within amino acids 260 - 310 of JAKMIP1.
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亚型
- IgG
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应用备注
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JAKMIP1 antibody can be used for detection of JAKMIP1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JAKMIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JAKMIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- JAKMIP1 (Janus Kinase and Microtubule Interacting Protein 1 (JAKMIP1))
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别名
- JAKMIP1
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背景
- JAKMIP1 Antibody: JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
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分子量
- Predicted: 69 kDa
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基因ID
- 152789
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NCBI登录号
- NP_653321
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UniProt
- Q96N16
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途径
- SARS-CoV-2 Protein Interactome
抗原
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