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MECR 抗体 (C-Term)

This anti-MECR antibody is a 兔 多克隆 antibody detecting MECR in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991794
发货至: 中国

Quick Overview for MECR 抗体 (C-Term) (ABIN6991794)

抗原

See all MECR 抗体
MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 25
  • 2

克隆类型

  • 27
多克隆

标记

  • 16
  • 2
  • 2
  • 1
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This MECR antibody is un-conjugated

应用范围

  • 16
  • 10
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 300-350, C-Term

    特异性

    At least two isoforms of MECR are known to exist, this antibody will detect both isoforms.

    纯化方法

    MECR Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal MECR antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MECR. The immunogen is located within amino acids 300 - 350 of MECR.

    亚型

    IgG
  • 应用备注

    MECR antibody can be used for detection of MECR by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MECR Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MECR antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    MECR (Mitochondrial Trans-2-Enoyl-CoA Reductase (MECR))

    别名

    MECR

    背景

    MECR Antibody: The mitochondrial trans-2-enoyl-CoA reductase (MECR), was initially identified as nuclear receptor-binding factor 1 (NRBF1), which can interact with a multitude of nuclear hormone receptors in the presence of the respective ligands. MECR has been shown to be part of the mitochondrial fatty acid synthesis (FAS II) system and to catalyze the NAPDH-dependent reduction of 2-enoyl thioesters, generating saturated acyl-groups. Overexpression of this gene in transgenic mice can lead to cardiac abnormalities, suggesting that inappropriate expression of genes of FAS II can result in the development of hereditary cardiomyopathy.

    分子量

    Predicted: 41 kDa

    基因ID

    51102

    NCBI登录号

    NP_057095

    UniProt

    Q9BV79
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