CHCHD6 抗体 (N-Term)
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北京 101111
Quick Overview for CHCHD6 抗体 (N-Term) (ABIN6991790)
抗原
See all CHCHD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-70, N-Term
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特异性
- CHCHD6 is predicted to not cross-react to other members of the CHCHD family.
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纯化方法
- CHCHD6 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6. The immunogen is located within amino acids 20 - 70 of CHCHD6.
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亚型
- IgG
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anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (Internal Region) antibody
CHCHD6 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 135-235) antibodyCHCHD6 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 1-235) antibodyCHCHD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (N-Term) antibodyCHCHD6 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 95-144) antibodyCHCHD6 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6) (AA 69-118) antibodyCHCHD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CHCHD6 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CHCHD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CHCHD6 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 6 (CHCHD6))
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别名
- CHCHD6
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背景
- CHCHD6 Antibody: CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
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分子量
- Predicted: 26 kDa
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基因ID
- 84303
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NCBI登录号
- NP_115719
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UniProt
- Q9BRQ6
抗原
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