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TSPY1S (C-Term) 抗体

适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991789
发货至: 中国
  • 抗原
    TSPY1S
    抗原表位
    C-Term
    适用
    人, 小鼠
    宿主
    克隆类型
    多克隆
    应用范围
    ELISA, Western Blotting (WB)
    特异性
    TSPY1S antibody is human and mouse reactive. At least three isoforms of TSPY1 are known to exist, this antibody will detect only TSPY1S
    纯化方法
    TSPY1S Antibody is affinity chromatography purified via peptide column.
    免疫原
    Rabbit polyclonal TSPY1S antibody was raised against a 13 amino acid peptide near the carboxy terminus of human TSPY1S. The immunogen is located within the last 50 amino acids of TSPY1S.
    亚型
    IgG
  • 应用备注
    TSPY1S antibody can be used for detection of TSPY1S by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TSPY1S Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TSPY1S antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TSPY1S
    背景
    TSPY1S Antibody: Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome that has been associated with gonadoblastoma. Recent experiments have shown that in androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family that acts as a ligand-inducible transcription factor, suggesting that TSPY1 is a repressor of cell proliferation in germ-cell tumors and potentially in normal gonadal cells during early development. Two distinct isoforms of TSPY1, TSPY1L and TSPY1S, are known to exist.
    分子量
    32 kDa
    基因ID
    7258
    NCBI登录号
    NP_001184171
    UniProt
    Q01534
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