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WIPI2 抗体 (N-Term)

This anti-WIPI2 antibody is a 兔 多克隆 antibody detecting WIPI2 in WB 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN6991783
发货至: 中国

Quick Overview for WIPI2 抗体 (N-Term) (ABIN6991783)

抗原

See all WIPI2 抗体
WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

适用

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人, 大鼠

宿主

  • 34
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克隆类型

  • 34
  • 14
多克隆

标记

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This WIPI2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 12
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    N-Term

    特异性

    WIPI2 antibody is human and rat reactive. Multiple isoforms of WIPI2 are known to exist. WIPI2 antibody is predicted to not cross-react with WIPI1.

    纯化方法

    WIPI2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal WIPI2 antibody was raised against a 17 amino acid peptide near the amino terminus of human WIPI2. The immunogen is located within the first 50 amino acids of WIPI2.

    亚型

    IgG
  • 应用备注

    WIPI2 antibody can be used for detection of WIPI2 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    WIPI2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    WIPI2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2 (WIPI2))

    别名

    WIPI2

    背景

    WIPI2 Antibody: WD repeat proteins play a role in many essential biologic functions, regulating the assembly of multiprotein complexes by presenting a beta-propeller platform for simultaneous and reversible protein-protein interactions. WIPI2, also known as ATG18B or ATG21, is a human homolog to yeast ATG18 and contains three WD repeats and has a 7-bladed propeller structure with a conserved motif that facilitates its interaction with other proteins. It is recruited to early autophagosomal structures along with Atg16L and ULK1 and is required for the formation of LC3-positive autophagosomes. Along with the highly related WIPI1, WIPI2 is found at the plasma membrane in addition to autophagosomal membranes.

    分子量

    50 kDa

    基因ID

    26100

    NCBI登录号

    NP_056425

    UniProt

    Q9Y4P8
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