PANX1 抗体 (N-Term)
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Quick Overview for PANX1 抗体 (N-Term) (ABIN6991780)
抗原
See all PANX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120, N-Term
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特异性
- Two transcript variants encoding different isoforms have been found for this gene.
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纯化方法
- PANX1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1. The immunogen is located within amino acids 70 - 120 of PANX1.
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亚型
- IgG
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应用备注
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PANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PANX1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PANX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PANX1 (Pannexin 1 (PANX1))
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别名
- PANX1
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背景
- PANX1 Antibody: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
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分子量
- 47 kDa
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基因ID
- 24145
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NCBI登录号
- NP_056183
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UniProt
- Q96RD7
抗原
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