PLA1A 抗体 (C-Term)
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北京 101111
Quick Overview for PLA1A 抗体 (C-Term) (ABIN6991764)
抗原
See all PLA1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 380-430, C-Term
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特异性
- At least three isoforms of PLA1A are known to exist, this antibody will detect all three isoforms.
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纯化方法
- PLA1A Antibody is affinity chromatography purified via peptide column.
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免疫原
- PLA1A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human PLA1A. The immunogen is located within amino acids 380 - 430 of PLA1A.
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亚型
- IgG
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anti-Phospholipase A1 Member A (PLA1A) (AA 309-452) antibody
PLA1A 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (AA 293-398) antibodyPLA1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (AA 1-456) antibodyPLA1A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (C-Term) antibodyPLA1A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (AA 241-340) antibodyPLA1A 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (Internal Region) antibodyPLA1A 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (AA 1-456) antibodyPLA1A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (AA 148-295) antibodyPLA1A 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase A1 Member A (PLA1A) (Middle Region) antibodyPLA1A 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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PLA1A antibody can be used for detection of PLA1A by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PLA1A Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PLA1A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PLA1A (Phospholipase A1 Member A (PLA1A))
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别名
- PLA1A
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背景
- PLA1A Antibody: PLA1A is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine (PS) in liposomes and can also hydrolyze PS in apoptotic cells and activate platelets where the resulting 2-acyl-lysophosphatidylserine acts as a lipid mediator for mast cells, T cells, and neural cells, suggesting that a major function of PLA1A may be the production of lysophospholipid mediators. PLA1A is upregulated in rat peripheral blood cells bearing long-term surviving cardiac allograft. PLA1A is also expressed in human THP-1-derived macrophages and this expression is upregulated in cells treated with lipopolysaccharide, a TLR4 ligand. This upregulation is inhibited with corticosteroids, which are often used at high dosages to suppress chronic allograft rejection.
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分子量
- 50 kDa
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基因ID
- 51365
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NCBI登录号
- NP_056984
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UniProt
- Q53H76
抗原
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