PLAGL2 抗体 (N-Term)
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北京 101111
Quick Overview for PLAGL2 抗体 (N-Term) (ABIN6991761)
抗原
See all PLAGL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90, N-Term
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特异性
- At least two isoforms are known to exist.
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纯化方法
- PLAGL2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PLAGL2 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human PLAGL2. The immunogen is located within amino acids 40 - 90 of PLAGL2.
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亚型
- IgG
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应用备注
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PLAGL2 antibody can be used for detection of PLAGL2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PLAGL2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PLAGL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PLAGL2 (Pleiomorphic Adenoma Gene-Like 2 (PLAGL2))
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别名
- PLAGL2
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背景
- PLAGL2 Antibody: The PLAG (Pleiomorphic adenoma gene) family of zinc finger proteins include PLAG1, ZAC1 and PLAG-like 2 (PLAGL2). PLAG1 is the target gene for the pleiomorphic adenomas of the salivary gland. ZAC1 (PLAGL1) concomitantly controls apoptosis and cell cycle arrest through separate pathways. ZAC1 also acts as a transcriptional cofactor for nuclear receptors. PLAGL2 belongs to the krueppel C2H2-type zinc-finger protein family and contains 6 C2H2-type zinc fingers. It functions as a positive regulator of transcription and localizes to the nucleus. PLAGL2 is ubiquitously expressed with particular abundance in spleen, lung and testis, where it may be involved in cell cycle arrest and apoptosis of tumor cells.
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分子量
- 55 kDa
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基因ID
- 5326
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NCBI登录号
- NP_002648
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UniProt
- Q9UPG8
抗原
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