Myc Target 1 抗体 (C-Term)
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北京 101111
Quick Overview for Myc Target 1 抗体 (C-Term) (ABIN6991752)
抗原
See all Myc Target 1 (MYCT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- At least two isoforms of MYCT1 are known to exist, this antibody will detect both isoforms.
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纯化方法
- MYCT1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1.
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亚型
- IgG
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anti-Myc Target 1 (MYCT1) (AA 21-100) antibody
MYCT1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myc Target 1 (MYCT1) (AA 95-144) antibodyMYCT1 适用: 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Myc Target 1 (MYCT1) (AA 135-163), (C-Term) antibodyMYCT1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB28146 unconjugated
anti-Myc Target 1 (MYCT1) (AA 142-171), (C-Term) antibodyMYCT1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MYCT1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MYCT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Myc Target 1 (MYCT1)
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别名
- MYCT1
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背景
- MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
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分子量
- 26 kDa
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基因ID
- 80177
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NCBI登录号
- NP_079383
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UniProt
- Q8N699
抗原
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