ATG2B 抗体 (N-Term)
Quick Overview for ATG2B 抗体 (N-Term) (ABIN6991740)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 450-500, N-Term
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特异性
- ATG2B antibody is predicted to not cross-react with other ATG2A.
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纯化方法
- ATG2B Antibody is affinity chromatography purified via peptide column.
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免疫原
- ATG2B antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ATG2B. The immunogen is located within amino acids 450 - 500 of ATG2B.
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亚型
- IgG
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anti-Autophagy Related 2B (ATG2B) (AA 1357-1536) antibody
ATG2B 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (N-Term) antibodyATG2B 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (AA 1360-1600) antibodyATG2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Autophagy Related 2B (ATG2B) (AA 118-146), (N-Term) antibodyATG2B 适用: 人 WB 宿主: 兔 Polyclonal RB33277 unconjugated
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应用备注
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ATG2B antibody can be used for detection of ATG2B by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATG2B Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATG2B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ATG2B (Autophagy Related 2B (ATG2B))
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别名
- ATG2B
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背景
- ATG2B Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy family of proteins is ATG2B, one of two homologs of ATG2 that is essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Relatively high rates of ATG2B mutations were observed in gastric and colorectal carcinomas, suggesting that deregulating the autophagy process may contribute to cancer development.
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分子量
- 229 kDa
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基因ID
- 55102
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NCBI登录号
- NP_060506
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UniProt
- Q96BY7
抗原
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