TOX 抗体 (N-Term)
Quick Overview for TOX 抗体 (N-Term) (ABIN6991735)
抗原
See all TOX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180, N-Term
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特异性
- No alternatively spliced transcript variants have been observed.
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纯化方法
- TOX Antibody is affinity chromatography purified via peptide column.
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免疫原
- TOX antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human TOX. The immunogen is located within amino acids 130 - 180 of TOX.
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亚型
- IgG
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anti-Thymus High Mobility Group Box Protein (TOX) (AA 141-288) antibody
TOX 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) antibodyTOX 适用: 小鼠, 大鼠 IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Thymus High Mobility Group Box Protein (TOX) (N-Term) antibodyTOX 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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TOX antibody can be used for detection of TOX by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TOX Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TOX antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TOX (Thymus High Mobility Group Box Protein (TOX))
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别名
- TOX
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背景
- TOX Antibody: TOX (thymocyte selection-associated high mobility group (HMG) box protein) is a member of the HMG box family of DNA-binding proteins and likely plays a role in the regulation of T-cell development. It is a 526 amino acid nuclear protein and the expression of TOX is upregulated by pre-T cell receptor (pre-TCR) and TCR activation in immature thymocytes. TOX-mediated positive selection is associated with up-regulation of RUNX3 and is calcineurin dependent. TOX-dependent transition to the CD4+CD8 stage is required for development of class II major histocompatibility complex-specific T cells.
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分子量
- 58 kDa
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基因ID
- 9760
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NCBI登录号
- NP_055544
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UniProt
- O94900
抗原
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