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BCL6 抗体 (AA 370-420)

This anti-BCL6 antibody is a 兔 多克隆 antibody detecting BCL6 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991734
发货至: 中国

Quick Overview for BCL6 抗体 (AA 370-420) (ABIN6991734)

抗原

See all BCL6 抗体
BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

适用

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人, 小鼠, 大鼠

宿主

  • 102
  • 94
  • 1

克隆类型

  • 136
  • 61
多克隆

标记

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This BCL6 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 370-420

    特异性

    Three alternatively spliced transcript variants have been observed

    纯化方法

    BCL6 Antibody is affinity chromatography purified via peptide column.

    免疫原

    BCL6 antibody was raised against an 18 amino acid synthetic peptide near the center of human BCL6. The immunogen is located within amino acids 370 - 420 of BCL6.

    亚型

    IgG
  • 应用备注

    BCL6 antibody can be used for detection of BCL6 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    BCL6 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    BCL6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

    别名

    BCL6

    背景

    BCL6 Antibody: BCL6 was first identified as a proto-oncogene in diffuse large B cell lymphoma. BCL6, a transcriptional repressor, plays an important role in lymphomagenesis. It binds Stat recognition-like DNA elements and is required for affinity maturation of mature B cells in germinal centers and Th1/Th2 differentiation, a process that critically depends on BCL6-mediated transcriptional repression of p53. BCL6 is a pharmacological target for eradication of leukemia-initiating cells in chronic myeloid leukemia (CML).

    分子量

    78 kDa

    基因ID

    604

    NCBI登录号

    NP_001124317

    UniProt

    P41182

    途径

    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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