Western Blotting (WB), ELISA, Immunofluorescence (IF)
特异性
Two alternatively spliced transcript variants have been observed.
纯化方法
ANG Antibody is affinity chromatography purified via peptide column.
免疫原
ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG. The immunogen is located within amino acids 70 - 120 of ANG.
ANG antibody can be used for detection of ANG by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
ANG Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
ANG antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ALS9 antibody, HEL168 antibody, RNASE4 antibody, RNASE5 antibody, ANG antibody, AI385586 antibody, Ang1 antibody, Rnase5 antibody, Rnase5a antibody, ANG1 antibody, angiogenin antibody, angiogenin, ribonuclease, RNase A family, 5 antibody, ribonuclease A family member k6 antibody, ANG antibody, Ang antibody, RNASE6 antibody
背景
ANG Antibody: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.