NDFIP1 抗体 (N-Term)
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Quick Overview for NDFIP1 抗体 (N-Term) (ABIN6991731)
抗原
See all NDFIP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- NDFIP1 antibody is predicted to not cross-react with NDFIP2.
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纯化方法
- NDFIP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NDFIP1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NDFIP1. The immunogen is located within the first 50 amino acids of NDFIP1.
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亚型
- IgG
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应用备注
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NDFIP1 antibody can be used for detection of NDFIP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NDFIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NDFIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- NDFIP1 (Nedd4 Family Interacting Protein 1 (NDFIP1))
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别名
- NDFIP1
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背景
- NDFIP1 Antibody: The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.
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分子量
- 24 kDa
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基因ID
- 80762
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NCBI登录号
- NP_085048
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UniProt
- Q9BT67
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途径
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Negative Regulation of Transporter Activity
抗原
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