KCP 抗体 (C-Term)
This anti-KCP antibody is a 兔 多克隆 antibody detecting KCP in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
Quick Overview for KCP 抗体 (C-Term) (ABIN6991728)
抗原
See all KCP 抗体
KCP
(Kielin/Chordin-Like Protein (KCP))
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
This KCP antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- AA 1320-1370, C-Term
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特异性
- At least two isoforms of CRIM2 are known to exist, this antibody will only detect the larger isoform. CRIM2 antibody is predicted to not cross-react with CRIM1.
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纯化方法
- CRIM2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CRIM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2. The immunogen is located within amino acids 1320 - 1370 of CRIM2.
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亚型
- IgG
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anti-Kielin/Chordin-Like Protein (KCP) (N-Term) antibody
KCP 适用: 人, 大鼠, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Kielin/Chordin-Like Protein (KCP) (C-Term) antibodyKCP 适用: 人, 大鼠, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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CRIM2 antibody can be used for detection of CRIM2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CRIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CRIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- KCP (Kielin/Chordin-Like Protein (KCP))
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别名
- CRIM2
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背景
- CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β,1, suppressing activin- and TGF-β,1-dependent transcription.
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基因ID
- 375616
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NCBI登录号
- NP_001129386
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UniProt
- Q6ZWJ8
抗原
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