DDX60 抗体 (AA 1140-1190)
This anti-DDX60 antibody is a 兔 多克隆 antibody detecting DDX60 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for DDX60 抗体 (AA 1140-1190) (ABIN6991720)
抗原
See all DDX60 抗体
DDX60
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DDX60 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF)
-
-
抗原表位
- AA 1140-1190
-
特异性
- At least three isoforms of DDX60 are known to exist, this antibody will detect all three isoforms.
-
纯化方法
- DDX60 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- DDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60. The immunogen is located within amino acids 1140 - 1190 of DDX60.
-
亚型
- IgG
-
-
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60) (AA 1-183) antibody
DDX60 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60) (Middle Region) antibodyDDX60 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
DDX60 antibody can be used for detection of DDX60 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- DDX60 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- DDX60 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- DDX60 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
-
别名
- DDX60
-
背景
- DDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
-
分子量
-
Predicted: 125, 185, 188 kDa
Observed: 190 kDa -
基因ID
- 55601
-
NCBI登录号
- NP_060101
-
UniProt
- Q8IY21
抗原
-
You are here:
