DDX60 抗体 (AA 1140-1190)
This anti-DDX60 antibody is a 兔 多克隆 antibody detecting DDX60 in WB, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991720
发货至:
中国
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Contact Info
Our Local Distributor
中国
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北京 101111
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Quick Overview for DDX60 抗体 (AA 1140-1190) (ABIN6991720)
抗原
See all DDX60 抗体
DDX60
(DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This DDX60 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF)
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抗原表位
- AA 1140-1190
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特异性
- At least three isoforms of DDX60 are known to exist, this antibody will detect all three isoforms.
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纯化方法
- DDX60 Antibody is affinity chromatography purified via peptide column.
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免疫原
- DDX60 antibody was raised against a 17 amino acid synthetic peptide near the center of human DDX60. The immunogen is located within amino acids 1140 - 1190 of DDX60.
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亚型
- IgG
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60) (AA 1-183) antibody
DDX60 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60) (Middle Region) antibodyDDX60 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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DDX60 antibody can be used for detection of DDX60 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DDX60 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DDX60 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DDX60 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 60 (DDX60))
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别名
- DDX60
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背景
- DDX60 Antibody: DDX60 is a DEXD/H Box RNA helicase and the human homolog of the S. cerevisiae Ski2, a cofactor of RNA exosome. Expression of DDX60 increases after viral infection and binds to endogenous RIG-I, a cytoplasmic viral RNA sensor, as well as other RIG-I-like receptors such as MDA5 and LGP2. These proteins activate TBK1 and IKK-e, signaling IRF3 and NF-kB-responsive genes in the innate immune response pathway. DDX60 is required for the RIG-I- or MDA5-dependent response to viral infection, but is dispensable for TLR3-mediated signaling.
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分子量
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Predicted: 125, 185, 188 kDa
Observed: 190 kDa -
基因ID
- 55601
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NCBI登录号
- NP_060101
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UniProt
- Q8IY21
抗原
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