CENPW 抗体 (N-Term)
This anti-CENPW antibody is a 兔 多克隆 antibody detecting CENPW in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for CENPW 抗体 (N-Term) (ABIN6991719)
抗原
See all CENPW 抗体
CENPW
(Centromere Protein W (CENPW))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This CENPW antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA
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抗原表位
- N-Term
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特异性
- At least three isoforms of CENPW are known to exist, this antibody will detect all three isoforms.
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纯化方法
- CENPW Antibody is affinity chromatography purified via peptide column.
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免疫原
- CENPW antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CENPW. The immunogen is located within the first 50 amino acids of CENPW.
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亚型
- IgG
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anti-Centromere Protein W (CENPW) (N-Term) antibody
CENPW 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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CENPW antibody can be used for detection of CENPW by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CENPW Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CENPW antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CENPW (Centromere Protein W (CENPW))
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别名
- CENPW
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背景
- CENPW Antibody: CENPW was initially identified as a gene that was upregulated in multiple cancers, and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes. It was later found to be a nuclear protein that associated with CENPT, a component of CENPA nucleosome complex in the centromere, and is required for proper kinetochore function. CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin, also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase. Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis, suggesting that high levels of CENPW induces apoptotic cell death.
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基因ID
- 387103
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NCBI登录号
- NP_001012525
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UniProt
- Q5EE01
抗原
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